1. Mandl F.A., Kirsch V.C., Ugur I., Kunold E., Vomacka J., Fetzer C., Schneider S., Richter K., Fuchs T.M., Antes I., Sieber S.A. Natural product inspired amino-epoxybenzoquinones kill members of the gram-negative pathogen Salmonella by attenuating cellular stress response. Angew Chem Int Edit. 2016; accepted.
  2. Schneider M., Rosam M., Glaser M., Patronov A., Shah H., Back K.C., Daake M.A., Buchner J., Antes I. BiPPred: Combined sequence- and structure-based prediction of peptide binding to the Hsp70 chaperone BiP. Proteins 2016;84(10):1390-1407.
  3. Ruhl G., Niedl A.G., Patronov A., Siewert K., Pinkert S., Kalemanov M., Friese M.A., Attfield K.E., Antes I., Hohlfeld R., Dornmair K. Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor. Neurol Neuroimmunol Neuroinflamm 2016;3(4):e241.
  4. Duell E.R., Glaser M., Le Chapelain C., Antes I., Groll M., Huber E.M. Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA. ACS Chem Biol 2016;11(4):1082-1089.
  5. Bujotzek A., Dunbar J., Lipsmeier F., Schafer W., Antes I., Deane C.M., Georges G. Prediction of VH-VL domain orientation for antibody variable domain modeling. Proteins 2015;83(4):681-695.
  6. Welsch C., Haselow K., Gouttenoire J., Schneider M., Morikawa K., Martinez Y., Susser S., Sarrazin C., Zeuzem S., Antes I., Moradpour D., Lange C.M. Hepatitis C virus variants resistant to macrocyclic NS3-4A inhibitors subvert IFN-beta induction by efficient MAVS cleavage. J Hepatol 2015;62(4):779-784.
  7. Hackl M.W., Lakemeyer M., Dahmen M., Glaser M., Pahl A., Lorenz-Baath K., Menzel T., Sievers S., Bottcher T., Antes I., Waldmann H., Sieber S.A. Phenyl Esters Are Potent Inhibitors of Caseinolytic Protease P and Reveal a Stereogenic Switch for Deoligomerization. J Am Chem Soc 2015;137(26):8475-8483.
  8. Zachmann M., Mathias G., Antes I. Parameterization of the Hamiltonian Dielectric Solvent (HADES) Reaction-Field Method for the Solvation Free Energies of Amino Acid Side-Chain Analogs. Chemphyschem 2015;16(8):1739-1749.
  9. Hoffmann T., Krackhardt A.M., Antes I. Quantitative Analysis of the Association Angle between T-cell Receptor Valpha/Vbeta Domains Reveals Important Features for Epitope Recognition. PLoS Comput Biol 2015;11(7):e1004244.
  10. Bujotzek A., Fuchs A., Qu C., Benz J., Klostermann S., Antes I., Georges G. MoFvAb: Modeling the Fv region of antibodies. MAbs 2015;7(5):838-852.
  11. Eirich J., Braig S., Schyschka L., Servatius P., Hoffmann J., Hecht S., Fulda S., Zahler S., Antes I., Kazmaier U., Sieber S.A., Vollmar A.M. A small molecule inhibits protein disulfide isomerase and triggers the chemosensitization of cancer cells. Angew Chem Int Ed Engl 2014;53(47):12960-12965.
  12. Yamane D., McGivern D.R., Wauthier E., Yi M., Madden V.J., Welsch C., Antes I., Wen Y., Chugh P.E., McGee C.E., Widman D.G., Misumi I., Bandyopadhyay S., Kim S., Shimakami T., Oikawa T., Whitmire J.K., Heise M.T., Dittmer D.P., Kao C.C., Pitson S.M., Merrill A.H., Jr., Reid L.M., Lemon S.M. Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation. Nat Med 2014;20(8):927-935.
  13. Gross S., Nguyen F., Bierschenk M., Sohmen D., Menzel T., Antes I., Wilson D.N., Bach T. Amythiamicin D and related thiopeptides as inhibitors of the bacterial elongation factor EF-Tu: modification of the amino acid at carbon atom C2 of ring C dramatically influences activity. ChemMedChem 2013;8(12):1954-1962.
  14. Marcinowski M., Rosam M., Seitz C., Elferich J., Behnke J., Bello C., Feige M.J., Becker C.F., Antes I., Buchner J. Conformational selection in substrate recognition by Hsp70 chaperones. J Mol Biol 2013;425(3):466-474.
  15. Welsch C., Schweizer S., Shimakami T., Domingues F.S., Kim S., Lemon S.M., Antes I. Ketoamide resistance and hepatitis C virus fitness in val55 variants of the NS3 serine protease. Antimicrob Agents Chemother 2012;56(4):1907-1915.
  16. Frauer C., Hoffmann T., Bultmann S., Casa V., Cardoso M.C., Antes I., Leonhardt H. Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. PLoS One 2011;6(6):e21306.
  17. Bleif S., Hannemann F., Lisurek M., von Kries J.P., Zapp J., Dietzen M., Antes I., Bernhardt R. Identification of CYP106A2 as a regioselective allylic bacterial diterpene hydroxylase. Chembiochem 2011;12(4):576-582.
  18. Antes I. DynaDock: A new molecular dynamics-based algorithm for protein-peptide docking including receptor flexibility. Proteins 2010;78(5):1084-1104.
  19. Welker M.W., Welsch C., Meyer A., Antes I., Albrecht M., Forestier N., Kronenberger B., Lengauer T., Piiper A., Zeuzem S., Sarrazin C. Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper. Protein Sci 2010;19(7):1327-1336.
  20. Roomp K., Antes I., Lengauer T. Predicting MHC class I epitopes in large datasets. BMC Bioinformatics 2010;11:90.
  21. Hartmann C., Antes I., Lengauer T. Docking and scoring with alternative side-chain conformations. Proteins 2009;74(3):712-726.
  22. Welsch C., Domingues F.S., Susser S., Antes I., Hartmann C., Mayr G., Schlicker A., Sarrazin C., Albrecht M., Zeuzem S., Lengauer T. Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus. Genome Biol 2008;9(1):R16.
  23. Lucas S., Heim R., Negri M., Antes I., Ries C., Schewe K.E., Bisi A., Gobbi S., Hartmann R.W. Novel aldosterone synthase inhibitors with extended carbocyclic skeleton by a combined ligand-based and structure-based drug design approach. J Med Chem 2008;51(19):6138-6149.
  24. Lisurek M., Simgen B., Antes I., Bernhardt R. Theoretical and experimental evaluation of a CYP106A2 low homology model and production of mutants with changed activity and selectivity of hydroxylation. Chembiochem 2008;9(9):1439-1449.
  25. Hartmann C., Antes I., Lengauer T. IRECS: a new algorithm for the selection of most probable ensembles of side-chain conformations in protein models. Protein Sci 2007;16(7):1294-1307.
  26. Antes I., Siu S.W., Lengauer T. DynaPred: a structure and sequence based method for the prediction of MHC class I binding peptide sequences and conformations. Bioinformatics 2006;22(14):e16-24.
  27. Heckmann-Pohl D.M., Bastian S., Altmeier S., Antes I. Improvement of the fungal enzyme pyranose 2-oxidase using protein engineering. J Biotechnol 2006;124(1):26-40.
  28. Voets M., Antes I., Scherer C., Muller-Vieira U., Biemel K., Marchais-Oberwinkler S., Hartmann R.W. Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis. J Med Chem 2006;49(7):2222-2231.
  29. Antes I., Merkwirth C., Lengauer T. POEM: Parameter Optimization using Ensemble Methods: application to target specific scoring functions. J Chem Inf Model 2005;45(5):1291-1302.
  30. Bojunga J., Welsch C., Antes I., Albrecht M., Lengauer T., Zeuzem S. Structural and functional analysis of a novel mutation of CYP21B in a heterozygote carrier of 21-hydroxylase deficiency. Hum Genet 2005;117(6):558-564.
  31. Ulmschneider S., Muller-Vieira U., Klein C.D., Antes I., Lengauer T., Hartmann R.W. Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase. J Med Chem 2005;48(5):1563-1575.
  32. Voets M., Antes I., Scherer C., Muller-Vieira U., Biemel K., Barassin C., Marchais-Oberwinkler S., Hartmann R.W. Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis. J Med Chem 2005;48(21):6632-6642.
  33. Gu W., Kofler M., Antes I., Freund C., Helms V. Alternative binding modes of proline-rich peptides binding to the GYF domain. Biochemistry 2005;44(17):6404-6415.
  34. Ulmschneider S., Muller-Vieira U., Mitrenga M., Hartmann R.W., Oberwinkler-Marchais S., Klein C.D., Bureik M., Bernhardt R., Antes I., Lengauer T. Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase. J Med Chem 2005;48(6):1796-1805.
  35. Crass T., Antes I., Basekow R., Bork P., Buning C., Christensen M., Claussen H., Ebeling C., Ernst P., Gailus-Durner V., Glatting K.H., Gohla R., Gossling F., Grote K., Heidtke K., Herrmann A., O'Keeffe S., Kiesslich O., Kolibal S., Korbel J.O., Lengauer T., Liebich I., van der Linden M., Luz H., Meissner K., von Mering C., Mevissen H.T., Mewes H.W., Michael H., Mokrejs M., Muller T., Pospisil H., Rarey M., Reich J.G., Schneider R., Schomburg D., Schulze-Kremer S., Schwarzer K., Sommer I., Springstubbe S., Suhai S., Thoppae G., Vingron M., Warfsmann J., Werner T., Wetzler D., Wingender E., Zimmer R. The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources. Bioinformatics 2004;20(2):268-270.
  36. Antes I., Chandler D., Wang H., Oster G. The unbinding of ATP from F1-ATPase. Biophys J 2003;85(2):695-706.
  37. Antes I., Thiel W., van Gunsteren W.F. Molecular dynamics simulations of photoactive yellow protein (PYP) in three states of its photocycle: a comparison with X-ray and NMR data and analysis of the effects of Glu46 deprotonation and mutation. Eur Biophys J 2002;31(7):504-520.
  38. Daura X., Antes I., van Gunsteren W.F., Thiel W., Mark A.E. The effect of motional averaging on the calculation of NMR-derived structural properties. Proteins 1999;36(4):542-555.
  39. Antes I., Thiel W. Adjusted connection atoms for combined quantum mechanical and molecular mechanical methods. Journal of Physical Chemistry A 1999;103(46):9290-9295.
  40. Antes I., Dapprich S., Frenking G., Schwerdtfeger P. Stability of group 11 carbonyl complexes Cl-M-CO (M=Cu, Ag, Au) (vol 35, pg 2089, 1996). Inorganic Chemistry 1997;36(1):128-128.
  41. Antes I., Dapprich S., Frenking G., Schwerdtfeger P. Stability of group 11 carbonyl complexes Cl-M-CO (M=Cu,Ag,Au). Inorganic Chemistry 1996;35(7):2089-2096.
  42. Antes I., Frenking G. Structure and bonding of the transition-metal methyl and phenyl compounds MCH(3) and MC(6)H(5) (M=Cu,Ag,Au) and M(CH3)(2) and M(C6H5)(2) (M=Zn,Cd,Hg). Organometallics 1995;14(9):4263-4268.
  43. Jubert C., Nowotny S., Kornemann D., Antes I., Tucker C.E., Knochel P. Stereodivergent additions of allylic chromium(III) reagents to aldehydes. Journal of Organic Chemistry 1992;57(24):6384-6386.